If you haven't checked out Google Reader, you should give it a look. I don't personally have a wealth of experience using other feed readers out there, but I've tried a few. The Google reader is non-intrusive for the most part. Most of the operations you'd want are close at hand and obvious (mark all as read, for example). They use tagging rather than folder structures, though they display your tags as folders. If you tag something as java, you can still tag it as technology; it will show up in both.
If you use Firefox 2.0, and you should, you'll find that they play really nice together. When browsing the web with Firfox you'll see a little 'RSS' box come up in your address bar. That box means that there is a feed for the site your looking at and you can subscribe to it. If you click on that box, Firefox will take you to a page where you chose where to add that subscription. If you choose Google Reader, google will come up and ask you if you'd like to add it to your google homepage (cool in it's own right, but not a good feed reader), or Google Reader. Clicking on Google Reader will take you into Reader, and will show you the new subscription at the bottom of your subscription view on the left (putting new stuff at the top would be better in my opinion). Your new subscription will also be the current view in the reader pane. Up at the top you can choose to label (I was calling it tags earlier, sorry) the current subscription for categorization.
So, if you haven't checked it out before, give it a look, it's pretty nice. Hell, if you don't like it it's not like you have to uninstall it or something :)